This chapter provides an overview of pedagogical issues, problems, and possibilities in global online classrooms, with a particular focus on the communication component. Discussions of pedagogical principles, problems, and possibilities are based on reflections of international collaborative projects conducted through a global educational network named 'Computer Pals Across the World” (CPAW), and are situated in important educational issues including context, commitment, collaboration and curriculum integration. It is hoped that these discussions will serve as a catalyst for further innovation and research in effective use of technology in global online classrooms.